Tissue Engineering for Regeneration

1 Hour 15 Minutes

Monday Session, 10:45 a.m.–12:15 p.m.

Program Track: Imaging and Emerging Technologies

Moderator: Purnima Kumar

Speakers: Sahar Ansari and Alireza Moshaverinia

The ultimate goal of bone tissue engineering is the regeneration of a construct that matches the physical and biological properties of the natural bone tissue. Repair and regeneration of craniofacial bone defects has widely been achieved with bone grafting procedures. However, there are several disadvantages associated with this treatment modality. An advantageous, alternative therapeutic option is bone regeneration using mesenchymal stem cells (MSCs). MSCs derived from orofacial tissues are attractive postnatal stem cells with self-renewal and multilineage differentiation capacity providing superior osteogenic properties. Furthermore, the neural crest origin of these MSCs makes them a better source for jawbone regeneration. In this session, alternative bone regenerative properties based on concepts of tissue engineering using stem cells and growth factors will be discussed.

Educational Objectives:

• Review the current treatment modality of craniofacial bone tissue regeneration.

• Discuss the potential disadvantages and limitation of bone grafting procedures.

• Discuss the latest developments in periodontal tissue regeneration and bone tissue engineering, using smart biomaterials and growth factors.

• Introduce novel treatment modalities for bone regenerative treatments based on stem cell therapy and tissue engineering concepts as futuristic therapies for patients.

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