Emerging Regenerative Approaches to Periodontal Reconstruction

Tuesday, Oct. 30
2 - 4 p.m.

Program Track: Tissue Engineering and Hard Tissue Reconstruction
Moderators: Jill Bashutski and Hidemi Kurihara
Speakers: William Giannobile, Bradley McAllister, and Shinya Murakami

Repair of alveolar bone defects caused by development abnormalities, trauma, or disease is a major goal of oralreconstructive therapy. The field of tissue engineering combines advances in materials, science, and biology to repair tissues and organs. One of the most promising treatments to stimulate periodontal regeneration is the use of cytokines and other growth factors. Over the past decade investigators have utilized growth factor biologics, barriers, and bone replacement grafts to restore lost tooth support due to damage of the alveolus. This presentation will highlight emerging technologies in cytokines such as Fibroblast Growth Factor (FGF-2), 3-D printing, bioprinting, biomaterials, and growth factor biologics for application to the clinical arena.

Educational Objectives:
• Identify the principles involved in tissue engineering of tooth- and implant-supporting periodontal structures such as bone, periodontal ligament, gingival, and cementum. 
• Gain the latest innovations in periodontal tissue engineering, including cytokine and stem cell therapies, as well as the mechanisms of action of growth factors to repair periodontal and dental implant bone defects. 
• Describe the modes of action, indications, and limitations of both patient-specific and implant-specific factors affecting treatment outcomes of regenerative therapies. 
• Determine the potential of new emerging therapies such as FGF-2, stem cells 3-D printing technology, and interactive scaffold matrices.